Osteopontin enhances the effect of treadmill training and promotes functional recovery after spinal cord injury

Osteopontin enhances the effect of treadmill training and promotes functional recovery after spinal cord injury

Abstract In this study, we examined the combined impact of osteopontin (OPN) and treadmill training on mice with spinal cord injury (SCI). OPN was overexpressed by injecting AAV9-SPP1-GFP into the sensorimotor cortex, followed by a left incomplete C5 crush injury two weeks later. Mice (Ex or Ex + OP...

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Bibliographic Details
Main Authors: Yunhang Wang, Hong Su, Juan Zhong, Zuxiong Zhan, Qin Zhao, Yuan Liu, Sen Li, Haiyan Wang, Ce Yang, Lehua Yu, Botao Tan, Ying Yin
Format: Article
Language:English
Published: Springer 2023-11-01
Series:Molecular Biomedicine
Subjects:
Osteopontin
Treadmill training
Functional recovery
Spinal cord injury
Online Access:https://doi.org/10.1186/s43556-023-00154-y

Internet

https://doi.org/10.1186/s43556-023-00154-y

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