Molecular features that predict the response to antimetabolite chemotherapies
Abstract Background Antimetabolite chemotherapeutic agents that target cellular metabolism are widely used in the clinic and are thought to exert their anti-cancer effects mainly through non-specific cytotoxic effects. However, patients vary dramatically with respect to treatment outcome, and the so...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-10-01
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Series: | Cancer & Metabolism |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40170-017-0170-3 |