Combination of thalidomide and Clostridium butyricum relieves chemotherapy-induced nausea and vomiting via gut microbiota and vagus nerve activity modulation

Combination of thalidomide and Clostridium butyricum relieves chemotherapy-induced nausea and vomiting via gut microbiota and vagus nerve activity modulation

Nausea and vomiting (CINV) are distressful and widespread side effects of chemotherapy, and additional efficient regimens to alleviate CINV are urgently needed. In the present study, colorectal cancer (CRC) mice model induced by Azoxymethane (AOM)/Dextran Sodium Sulfate (DSS) was employed to evaluat...

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Bibliographic Details
Main Authors: Xuanqi Zhao, Heng Wu, Ruizhe Zhu, Gaishuang Shang, Jing Wei, Haitao Shang, Puyuan Tian, Tingtao Chen, Hong Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
CINV
thalidomide
intestinal microecology
Clostridium butyricum
gut- brain axis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1220165/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1220165/full

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