Quantitative spatial evaluation of tumor-immune interactions in the immunotherapy setting of metastatic melanoma lymph nodes

Quantitative spatial evaluation of tumor-immune interactions in the immunotherapy setting of metastatic melanoma lymph nodes

IntroductionImmune cell infiltration into the tumor microenvironment is generally associated with favorable clinical outcomes in solid tumors. However, the dynamic interplay among distinct immune cell subsets within the tumor-immune microenvironment as it relates to clinical responses to immunothera...

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Bibliographic Details
Main Authors: Rachel L. G. Maus, Alexey A. Leontovich, Raymond M. Moore, Zachary Fogarty, Ruifeng Guo, Tara M. Davidson, Burak Tekin, Chathu Atherton, Jill M. Schimke, Betty A. Dicke, Benjamin J. Chen, Svetomir N. Markovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
multiplex immunofluorescence
melanoma
immunotherapy
spatial biology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1024039/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1024039/full

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