Concurrent targeting of glycolysis in bacteria and host cell inflammation in septic arthritis

Concurrent targeting of glycolysis in bacteria and host cell inflammation in septic arthritis

Abstract Intracellular infiltration of bacteria into host cells complicates medical and surgical treatment of bacterial joint infections. Unlike soft tissue infections, septic arthritis and infection‐associated inflammation destroy cartilage that does not regenerate once damaged. Herein, we show tha...

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Bibliographic Details
Main Authors: Hyuk‐Kwon Kwon, Kristin E Yu, Sean V Cahill, Kareme D Alder, Christopher M Dussik, Sang‐Hun Kim, Lokesh Sharma, Jungho Back, Irvin Oh, Francis Y Lee
Format: Article
Language:English
Published: Springer Nature 2022-12-01
Series:EMBO Molecular Medicine
Subjects:
dimethyl fumarate
glycolysis
inflammation
MRSA
septic arthritis
Online Access:https://doi.org/10.15252/emmm.202115284

Internet

https://doi.org/10.15252/emmm.202115284

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