Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment

Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment

Despite the significant outcomes attained by scientific research, breast cancer (BC) still represents the second leading cause of death in women. Estrogen receptor-positive (ER+) BC accounts for the majority of diagnosed BCs, highlighting the disruption of estrogenic signalling as target for first-l...

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Bibliographic Details
Main Authors: Silvia Gobbi, Silvia Martini, Riccardo Rozza, Angelo Spinello, Jessica Caciolla, Angela Rampa, Federica Belluti, Nadia Zaffaroni, Alessandra Magistrato, Alessandra Bisi
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
homoisoflavones
aromatase inhibitors
ERα ligands
multitarget
molecular dynamics
Online Access:https://www.mdpi.com/1420-3049/28/7/3047

Internet

https://www.mdpi.com/1420-3049/28/7/3047

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