Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid is associated with poor prognosis in idiopathic pulmonary fibrosis

Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid is associated with poor prognosis in idiopathic pulmonary fibrosis

Abstract Background The endogenous secretory receptor for advanced glycation end products (esRAGE) is a soluble isoform produced by alternative splicing of the RAGE gene. The isoform has anti-inflammatory properties due to its inhibition of the RAGE/ligand interaction and is reduced in the lung tiss...

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Bibliographic Details
Main Authors: Kakuhiro Yamaguchi, Hiroshi Iwamoto, Witold Mazur, Shinichiro Miura, Shinjiro Sakamoto, Yasushi Horimasu, Takeshi Masuda, Shintaro Miyamoto, Taku Nakashima, Shinichiro Ohshimo, Kazunori Fujitaka, Hironobu Hamada, Noboru Hattori
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Respiratory Research
Subjects:
esRAGE
IPF
BALF
Serum
Biomarker
Online Access:http://link.springer.com/article/10.1186/s12931-020-01410-3

Internet

http://link.springer.com/article/10.1186/s12931-020-01410-3

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