A systemized approach to investigate Ca2+ synchronization in clusters of human induced pluripotent stem-cell derived cardiomyocytes

A systemized approach to investigate Ca2+ synchronization in clusters of human induced pluripotent stem-cell derived cardiomyocytes

Induced pluripotent stem cell-derived cardiomyocytes (IPS-CM) are considered by many to be the cornerstone of future approaches to repair the diseased heart. However, current methods for producing IPS-CM typically yield highly variable populations with low batch-to-batch reproducibility. The underly...

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Bibliographic Details
Main Authors: Aled R Jones, David H Edwards, Michael J Cummins, Alan J Williams, Christopher H George
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Induced Pluripotent Stem Cells
synchronization
Calcium signalling
variability
phenotype
oscillation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00089/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00089/full

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