Noradrenergic dysfunction in Alzheimer’s disease

The brain noradrenergic system supplies the neurotransmitter norepinephrine throughout the brain via widespread efferent projections, and plays a pivotal role in modulating cognitive activities in the cortex. Profound noradrenergic degeneration in Alzheimer’s disease (AD) patients has been observed...

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Bibliographic Details
Main Authors: Mary eGannon, Pulin eChe, Yunjia eChen, Kai eJiao, Erik D Roberson, Qin eWang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00220/full