PAI-1 genetic polymorphisms influence septic patients' outcomes by regulating neutrophil activity

PAI-1 genetic polymorphisms influence septic patients' outcomes by regulating neutrophil activity

Abstract. Background:. Plasminogen activator inhibitor-1 (PAI-1) plays an important role in the pathophysiology of sepsis, but the exact mechanism remains debatable. In this study, we investigated the associations among the serum levels of PAI-1, the incidence of 4G/5G promoter PAI-1 gene polymorph...

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Bibliographic Details
Main Authors: Shaowei Jiang, Yang Wang, Liang Chen, Honghua Mu, Connor Meaney, Yiwen Fan, Janesh Pillay, Hairong Wang, Jincheng Zhang, Shuming Pan, Chengjin Gao, Yanjie Yin
Format: Article
Language:English
Published: Wolters Kluwer 2023-08-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000002316

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http://journals.lww.com/10.1097/CM9.0000000000002316

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