Kinsenoside Ameliorates Oxidative Stress-Induced RPE Cell Apoptosis and Inhibits Angiogenesis via Erk/p38/NF-κB/VEGF Signaling

Kinsenoside Ameliorates Oxidative Stress-Induced RPE Cell Apoptosis and Inhibits Angiogenesis via Erk/p38/NF-κB/VEGF Signaling

The pathological superoxidative condition that retinal pigment epithelium (RPE) cells experience contributed to the advancement of age-related macular degeneration (AMD), which was accompanied by significant neovascularization. Therefore, the discovery of novel pharmacological candidates to ameliora...

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Bibliographic Details
Main Authors: Xu Luo, Shengjie Gu, Yujiao Zhang, Jianhong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Pharmacology
Subjects:
age-related macular degeneration
oxidative stress
kinsenoside
retinal pigment epithelium
vascular endothelial growth factor
NF-κB
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00240/full

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http://journal.frontiersin.org/article/10.3389/fphar.2018.00240/full

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