Stepwise fate conversion of supporting cells to sensory hair cells in the chick auditory epithelium

Summary: In contrast to mammals, the avian cochlea, specifically the basilar papilla, can regenerate sensory hair cells, which involves fate conversion of supporting cells to hair cells. To determine the mechanisms for converting supporting cells to hair cells, we used single-cell RNA sequencing dur...

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Bibliographic Details
Main Authors: Mami Matsunaga, Ryosuke Yamamoto, Tomoko Kita, Hiroe Ohnishi, Norio Yamamoto, Takayuki Okano, Koichi Omori, Takayuki Nakagawa
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223001232