Endosomal Phosphatidylinositol-3-Phosphate-Associated Functions Are Dispensable for Establishment of the Cytomegalovirus Pre-Assembly Compartment but Essential for the Virus Growth

Endosomal Phosphatidylinositol-3-Phosphate-Associated Functions Are Dispensable for Establishment of the Cytomegalovirus Pre-Assembly Compartment but Essential for the Virus Growth

Murine cytomegalovirus (MCMV) initiates the stepwise establishment of the pre-assembly compartment (pre-AC) in the early phase of infection by the expansion of the early endosome (EE)/endosomal recycling compartment (ERC) interface and relocation of the Golgi complex. We depleted Vps34-derived phosp...

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Bibliographic Details
Main Authors: Marina Marcelić, Hana Mahmutefendić Lučin, Antonija Jurak Begonja, Gordana Blagojević Zagorac, Vanda Juranić Lisnić, Pero Lučin
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Life
Subjects:
cytomegalovirus
assembly compartment
early endosomes
endosomal recycling compartment
phosphatidylinositol-3-phosphate
Vps34
Online Access:https://www.mdpi.com/2075-1729/11/8/859

Internet

https://www.mdpi.com/2075-1729/11/8/859

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