Explicit calculation method for cell alignment in non-circular geometries

The alignment of spindle-shaped cells in two-dimensional geometries induces singular points called topological defects, at which the alignment angle of the cell cannot be defined. To control defects related to biological roles such as cell apoptosis, calculation methods for predicting the defect pos...

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Bibliographic Details
Main Authors: Hiroki Miyazako, Takaaki Nara
Format: Article
Language:English
Published: The Royal Society 2022-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.211663