Novel colistin-EDTA combination for successful eradication of colistin-resistant Klebsiella pneumoniae catheter-related biofilm infections

Novel colistin-EDTA combination for successful eradication of colistin-resistant Klebsiella pneumoniae catheter-related biofilm infections

Abstract Development of an effective therapy to overcome colistin resistance in Klebsiella pneumoniae, a common pathogen causing catheter-related biofilm infections in vascular catheters, has become a serious therapeutic challenge that must be addressed urgently. Although colistin and EDTA have succ...

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Bibliographic Details
Main Authors: Aye Mya Sithu Shein, Dhammika Leshan Wannigama, Paul G. Higgins, Cameron Hurst, Shuichi Abe, Parichart Hongsing, Naphat Chantaravisoot, Thammakorn Saethang, Sirirat Luk-in, Tingting Liao, Sumanee Nilgate, Ubolrat Rirerm, Naris Kueakulpattana, Matchima Laowansiri, Sukrit Srisakul, Netchanok Muhummudaree, Teerasit Techawiwattanaboon, Lin Gan, Chenchen Xu, Rosalyn Kupwiwat, Phatthranit Phattharapornjaroen, Rojrit Rojanathanes, Asada Leelahavanichkul, Tanittha Chatsuwan
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01052-5

Internet

https://doi.org/10.1038/s41598-021-01052-5

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