Advances on Cellular Clonotypic Immunity in Amyotrophic Lateral Sclerosis

Advances on Cellular Clonotypic Immunity in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disease, characterized by the progressive degeneration of the upper and lower motor neurons in the cortex and spinal cord. Although the pathogenesis of ALS remains unclear, evidence concerning the role of the clonotypic immune system is gr...

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Bibliographic Details
Main Authors: Giuseppe Schirò, Vincenzo Di Stefano, Salvatore Iacono, Antonino Lupica, Filippo Brighina, Roberto Monastero, Carmela Rita Balistreri
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Brain Sciences
Subjects:
Amyotrophic lateral sclerosis (ALS)
neurodegeneration
neuroinflammation
neuromuscular disease
autoimmunity
the clonotypic immune system
Online Access:https://www.mdpi.com/2076-3425/12/10/1412

Internet

https://www.mdpi.com/2076-3425/12/10/1412

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