RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter

RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter

Abstract Background Megakaryocytes (MKs) are platelet precursors, which arise from hematopoietic stem cells (HSCs). While MK lineage commitment and differentiation are accompanied by changes in gene expression, many factors that modulate megakaryopoiesis remain to be uncovered. Replication initiatio...

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Bibliographic Details
Main Authors: Jae-Hyun Jo, Jong-Uk Park, Yeong-Mu Kim, Seon-Mi Ok, Dong-Kyu Kim, Dong-Hyun Jung, Hye-Ji Kim, Hyun-A Seong, Hyo Je Cho, Jihoon Nah, Sangjune Kim, Haiqing Fu, Christophe E. Redon, Mirit I. Aladjem, Sang-Min Jang
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cell Communication and Signaling
Subjects:
Megakaryocytic differentiation
RepID
CRL4A
JARID1A
Online Access:https://doi.org/10.1186/s12964-023-01246-6

Internet

https://doi.org/10.1186/s12964-023-01246-6

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