Fenofibrate suppresses corneal neovascularization by regulating lipid metabolism through PPARα signaling pathway

Fenofibrate suppresses corneal neovascularization by regulating lipid metabolism through PPARα signaling pathway

Purpose: The purpose of this study was to explore the potential underlying mechanism of anti-vascular effects of peroxisome proliferator–activated receptor α (PPARα) agonist fenofibrate against corneal neovascularization (CNV) through the changes of lipid metabolism during CNV.Methods: A suture-indu...

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Bibliographic Details
Main Authors: Tong Zhou, Ke Yan, Yuhan Zhang, Linfangzi Zhu, Yi Liao, Xiaoxiang Zheng, Yongxiong Chen, Xiaoxin Li, Zuguo Liu, Zhaoqiang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Pharmacology
Subjects:
cornea
neovascularization
fenofibrate
PPARα
lipid metabolism
lipid deposition
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1000254/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1000254/full

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