Sertraline inhibits formalin-induced nociception and cardiovascular responses

Sertraline inhibits formalin-induced nociception and cardiovascular responses

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The objective of the present study was to determine the antihyperalgesic effect of sertraline, measured indirectly by the changes of sciatic afferent nerve activity, and its effects on cardiorespiratory parameters, using the model of formalin-induced inflammatory nociception in anesthetized rats. Se...

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Bibliographic Details
Main Authors: C.H. Santuzzi, H.A. Futuro Neto, J.G.P. Pires, W.L.S. Gonçalves, R.V. Tiradentes, S.A. Gouvea, G.R. Abreu
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Sertraline
Formalin-induced pain
Antinociceptive effect
Cardiovascular system
Sciatic nerve activity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000100008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000100008

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