Abietane Diterpenoids Isolated from <i>Torreya nucifera</i> Disrupt Replication of Influenza Virus by Blocking the Phosphatidylinositol-3-Kinase (PI3K)-Akt and ERK Signaling Pathway

Abietane Diterpenoids Isolated from <i>Torreya nucifera</i> Disrupt Replication of Influenza Virus by Blocking the Phosphatidylinositol-3-Kinase (PI3K)-Akt and ERK Signaling Pathway

Although vaccines and antiviral drugs are available, influenza viruses continue to pose a significant threat to vulnerable populations globally. With the emergence of drug-resistant strains, there is a growing need for novel antiviral therapeutic approaches. We found that 18-hydroxyferruginol (<b...

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Bibliographic Details
Main Authors: Jaehoon Bae, Hyung-Jun Kwon, Ji Sun Park, Jinseok Jung, Young Bae Ryu, Woo Sik Kim, Ju Huck Lee, Jae-Ho Jeong, Jae Sung Lim, Woo Song Lee, Su-Jin Park
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Current Issues in Molecular Biology
Subjects:
abietane diterpenoids
<i>Torreya nucifera</i>
influenza virus
PI3K-Akt
viral replication
Online Access:https://www.mdpi.com/1467-3045/45/3/147

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https://www.mdpi.com/1467-3045/45/3/147

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