Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway

Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway

Abstract Background Despite radiotherapy ability to significantly improve treatment outcomes and survival in triple-negative breast cancer (TNBC) patients, acquired resistance to radiotherapy poses a serious clinical challenge. Protein disulfide isomerase exists in endoplasmic reticulum and plays an...

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Bibliographic Details
Main Authors: Jinqiu Tao, Cailin Xue, Meng Cao, Jiahui Ye, Yulu Sun, Hao Chen, Yinan Guan, Wenjie Zhang, Weijie Zhang, Yongzhong Yao
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Breast Cancer Research
Subjects:
PDIA4
TNBC
Apoptosis
Radiation resistance
TAXBP1 JNK
Online Access:https://doi.org/10.1186/s13058-023-01758-6

Internet

https://doi.org/10.1186/s13058-023-01758-6

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