NLRP3 Is Involved in Neutrophil Mobilization in Experimental Periodontitis

NLRP3 Is Involved in Neutrophil Mobilization in Experimental Periodontitis

The NLRP3 inflammasome is overexpressed in gingiva of periodontitis patients but its role remains unclear. In our study, we use a periodontitis mouse model of ligature, impregnated or not with Porphyromonas gingivalis, in WT or NLRP3 KO mice. After 28 days of induction, ligature alone provoked exace...

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Bibliographic Details
Main Authors: Banndith Cheat, Coralie Torrens, Asmaa Foda, Brigitte Baroukh, Jeremy Sadoine, Lotfi Slimani, Véronique Witko-Sarsat, Olivier Huck, Marjolaine Gosset, Jérôme Bouchet
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
periodontitis
NLRP3 inflammasome
inflammation
neutrophils
Porphyromonas gingivalis (P. gingivalis)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.839929/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.839929/full

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