Scavenger receptor class a plays a central role in mediating mortality and the development of the pro-inflammatory phenotype in polymicrobial sepsis.

Scavenger receptor class a plays a central role in mediating mortality and the development of the pro-inflammatory phenotype in polymicrobial sepsis.

Sepsis is a frequent complication in critical illness. The mechanisms that are involved in initiation and propagation of the disease are not well understood. Scavenger receptor A (SRA) is a membrane receptor that binds multiple polyanions such as oxidized LDL and endotoxin. Recent studies suggest th...

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Bibliographic Details
Main Authors: Tammy R Ozment, Tuanzhu Ha, Kevin F Breuel, Tiffany R Ford, Donald A Ferguson, John Kalbfleisch, John B Schweitzer, Jim L Kelley, Chuanfu Li, David L Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3469655?pdf=render

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http://europepmc.org/articles/PMC3469655?pdf=render

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