ET-1 receptor type B (ETBR) overexpression associated with ICAM-1 downregulation leads to inflammatory attenuation in experimental autoimmune myocarditis

ET-1 receptor type B (ETBR) overexpression associated with ICAM-1 downregulation leads to inflammatory attenuation in experimental autoimmune myocarditis

Background An experimental autoimmune myocarditis rat model was established by subcutaneous injection of porcine myocardial myosin (PCM). The effect of ET-1 receptor type B (ETBR) overexpression on autoimmune myocarditis was observed via tail vein injection of ETBR overexpression lentivirus in rats....

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Bibliographic Details
Main Authors: Peng Yang, Fangfei Li, Jiangfeng Tang, Qingshan Tian, Zhenzhong Zheng
Format: Article
Language:English
Published: PeerJ Inc. 2023-10-01
Series:PeerJ
Subjects:
ETBR
Autoimmune myocarditis
ICAM-1
Inflammation
Immune damage
Cardiac function
Online Access:https://peerj.com/articles/16320.pdf

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https://peerj.com/articles/16320.pdf

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