Mutation profile of acute myeloid leukaemia in a Chinese cohort by targeted next‐generation sequencing

Mutation profile of acute myeloid leukaemia in a Chinese cohort by targeted next‐generation sequencing

Abstract Background Acute myeloid leukaemia (AML) results from the clonal expansion of blast cells of myeloid origin driven by genomic defects. The advances in next‐generation sequencing (NGS) have allowed the identification of many mutated genes important in the pathogenesis of AML. Aims In this st...

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Bibliographic Details
Main Authors: Benny Man Wai Lit, Belinda B. Guo, Jacques A. J. Malherbe, Yok Lam Kwong, Wendy N. Erber
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Cancer Reports
Subjects:
Chinese AML
DNMT3A
mutation frequency
next‐generation sequencing
Online Access:https://doi.org/10.1002/cnr2.1573

Internet

https://doi.org/10.1002/cnr2.1573

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