Development of a Microwave-assisted Chemoselective Synthesis of Oxime-linked Sugar Linkers and Trivalent Glycoclusters

Development of a Microwave-assisted Chemoselective Synthesis of Oxime-linked Sugar Linkers and Trivalent Glycoclusters

A rapid, high-yielding microwave-mediated synthetic procedure was developed and optimized using a model system of monovalent sugar linkers, with the ultimate goal of using this method for the synthesis of multivalent glycoclusters. The reaction occurs between the aldehyde/ketone on the sugars and an...

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Bibliographic Details
Main Authors: Katherine McReynolds, Dustin Dimas, Grace Floyd, Kara Zeman
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Pharmaceuticals
Subjects:
Microwave reactions
chemoselective
oxime
aminooxy
glycoclusters
multivalent
Online Access:http://www.mdpi.com/1424-8247/12/1/39

Internet

http://www.mdpi.com/1424-8247/12/1/39

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