Fluid balance control in critically ill patients: results from POINCARE-2 stepped wedge cluster-randomized trial

Abstract Background In critically ill patients, positive fluid balance is associated with excessive mortality. The POINCARE-2 trial aimed to assess the effectiveness of a fluid balance control strategy on mortality in critically ill patients. Methods POINCARE-2 was a stepped wedge cluster open-label...

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Bibliographic Details
Main Authors: Pierre-Edouard Bollaert, Alexandra Monnier, Francis Schneider, Laurent Argaud, Julio Badie, Claire Charpentier, Ferhat Meziani, Michel Bemer, Jean-Pierre Quenot, Marie Buzzi, Hervé Outin, Cédric Bruel, Laurent Ziegler, Sébastien Gibot, Jean-Marc Virion, Camille Alleyrat, Guillaume Louis, Nelly Agrinier
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s13054-023-04357-1