Immunoreactivity of Sera From Low to Moderate Malaria-Endemic Areas Against Plasmodium vivax rPvs48/45 Proteins Produced in Escherichia coli and Chinese Hamster Ovary Systems

Immunoreactivity of Sera From Low to Moderate Malaria-Endemic Areas Against Plasmodium vivax rPvs48/45 Proteins Produced in Escherichia coli and Chinese Hamster Ovary Systems

P48/45 is a conserved gametocyte antigen involved in Plasmodium parasite fertilization. A recombinant Plasmodium vivax P48/45 (Pvs48/45) protein expressed in Escherichia coli (E. coli) was highly antigenic and immunogenic in experimental animals and elicited specific transmission-blocking (TB) antib...

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Bibliographic Details
Main Authors: Myriam Arévalo-Herrera, Kazutoyo Miura, Nora Cespedes, Carlos Echeverry, Eduardo Solano, Angélica Castellanos, Juan Sebastián Ramirez, Adolfo Miranda, Andrey V. Kajava, Carole Long, Giampietro Corradin, Sócrates Herrera
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
malaria
Plasmodium vivax
gametocytes
transmission blocking
Pvs48/45
vaccines
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.634738/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.634738/full

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