Antibody-drug conjugates and predictive biomarkers in advanced urothelial carcinoma

The use of antibody-drug conjugates (ADCs) is expanding in several malignancies, including urothelial carcinoma where two of these medications have been approved for use and several others remain under study. ADCs act by binding to specific cell surface proteins, delivering anticancer agents directl...

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Bibliographic Details
Main Authors: Sarah E. Fenton, David J. VanderWeele
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1069356/full