Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications

Triple-negative breast cancer (TNBC) accounts for ~15–20% of breast cancer (BC) and has a higher rate of early relapse and mortality compared to other subtypes. The Chemokine (C-C motif) ligand 5 (CCL5) and its signaling pathway have been linked to TNBC. We aimed to investigate the susceptibility an...

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Bibliographic Details
Main Authors: Jingxuan Shan, Aziz Chouchane, Younes Mokrab, Mohamad Saad, Salha Boujassoum, Rosalyn W. Sayaman, Elad Ziv, Noureddine Bouaouina, Yasmine Remadi, Sallouha Gabbouj, Jessica Roelands, Xiaojing Ma, Davide Bedognetti, Lotfi Chouchane
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
CCL5
CCL5 signaling genes
triple negative breast cancer
prognosis
susceptibility
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01328/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01328/full

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