Terbium to Quantum Dot FRET Bioconjugates for Clinical Diagnostics: Influence of Human Plasma on Optical and Assembly Properties

Terbium to Quantum Dot FRET Bioconjugates for Clinical Diagnostics: Influence of Human Plasma on Optical and Assembly Properties

Förster resonance energy transfer (FRET) from luminescent terbium complexes (LTC) as donors to semiconductor quantum dots (QDs) as acceptors allows extraordinary large FRET efficiencies due to the long Förster distances afforded. Moreover, time-gated detection permits an efficient suppression of aut...

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Bibliographic Details
Main Authors: Niko Hildebrandt, Juan B. Blanco-Canosa, Philip E. Dawson, Michael H. Stewart, Kimihiro Susumu, W. Russ Algar, Frank Morgner, Igor L. Medintz, Daniel Geißler, Stefan Stufler
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Sensors
Subjects:
FRET
quantum dots
terbium
luminescence lifetime
blood
plasma
clinical diagnostics
biotin
streptavidin
histidin
immunoassay
Online Access:http://www.mdpi.com/1424-8220/11/10/9667/

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http://www.mdpi.com/1424-8220/11/10/9667/

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