Synthesis, evaluation of the cytotoxicity, apoptosis induction in AGS cell line and gene expression and molecular modeling studies of novel tetrahydropyrimidine derivatives

Cancer is a complex disease that remains a leading cause of death worldwide owing to the lack of effective and efficient drugs. Compounds known as tetrahydropyrmidine have shown great potential as anti-cancer agents. Here, novel compounds based on tetrahydropyrimidine scaffold were successfully synt...

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Bibliographic Details
Main Authors: Saghi Sepehri, Yasin Panahi, Daniyal Abbasi, Mahsa Jafari, Vahed Adhami, Ghazaleh Farhadi
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223009103