Synthesis, evaluation of the cytotoxicity, apoptosis induction in AGS cell line and gene expression and molecular modeling studies of novel tetrahydropyrimidine derivatives
Cancer is a complex disease that remains a leading cause of death worldwide owing to the lack of effective and efficient drugs. Compounds known as tetrahydropyrmidine have shown great potential as anti-cancer agents. Here, novel compounds based on tetrahydropyrimidine scaffold were successfully synt...
Main Authors: | Saghi Sepehri, Yasin Panahi, Daniyal Abbasi, Mahsa Jafari, Vahed Adhami, Ghazaleh Farhadi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-01-01
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Series: | Arabian Journal of Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535223009103 |
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