Design Evaluation and Optimization of Population Pharmacokinetics Model Using an R Package PopED

The rising cost in drug development has led to continuous calls for more efficient and powerful design optimization and analysis tools for pkpd studies. More sophisticated models are increasingly used to reflect reality, and current models invariably include non-linear mixed effects models that freq...

Full description

Bibliographic Details
Main Authors: Howon Ryu, Weng Kee Wong
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Mathematics
Subjects:
Online Access:https://www.mdpi.com/2227-7390/11/21/4407