Targeting miR-181a/b in retinitis pigmentosa: implications for disease progression and therapy

Targeting miR-181a/b in retinitis pigmentosa: implications for disease progression and therapy

Abstract Background Retinitis pigmentosa (RP) is a genetically heterogeneous group of degenerative disorders causing progressive vision loss due to photoreceptor death. RP affects other retinal cells, including the retinal pigment epithelium (RPE). MicroRNAs (miRs) are implicated in RP pathogenesis,...

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Bibliographic Details
Main Authors: Bruna Lopes da Costa, Peter M. J. Quinn, Wen-Hsuan Wu, Siyuan Liu, Nicholas D. Nolan, Aykut Demirkol, Yi-Ting Tsai, Salvatore Marco Caruso, Thiago Cabral, Nan-Kai Wang, Stephen H. Tsang
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Cell & Bioscience
Subjects:
MicroRNAs
Metabolic reprogramming
Retinal pigment epithelium
Retinitis pigmentosa
Aerobic glycolysis
Online Access:https://doi.org/10.1186/s13578-024-01243-3

Internet

https://doi.org/10.1186/s13578-024-01243-3

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