Sirt1 inhibits resistin expression in aortic stenosis.

The development of human calcified aortic stenosis (AS) includes age-dependent processes that have been involved in atherosclerosis, such as infiltration of macrophages in aortic valves, which then promote production of many pro-inflammatory cytokines, including resistin. However, the molecular mech...

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Bibliographic Details
Main Authors: Sophie Carter, Stéphanie Miard, Catherine Roy-Bellavance, Louise Boivin, Zhuo Li, Philippe Pibarot, Patrick Mathieu, Frédéric Picard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3320872?pdf=render