A novel miR-0308-3p revealed by miRNA-seq of HBV-positive hepatocellular carcinoma suppresses cell proliferation and promotes G1/S arrest by targeting double CDK6/Cyclin D1 genes

A novel miR-0308-3p revealed by miRNA-seq of HBV-positive hepatocellular carcinoma suppresses cell proliferation and promotes G1/S arrest by targeting double CDK6/Cyclin D1 genes

Abstract Background Persistent infection with hepatitis B virus (HBV) accounts for the majority of hepatocellular carcinoma (HCC), but the molecular mechanisms underlying liver carcinogenesis are still not completely understood. Increasing evidence demonstrates that microRNAs (miRNAs) play significa...

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Bibliographic Details
Main Authors: Xiaoming Dai, Ruixue Huang, Sai Hu, Yao Zhou, Xiaoya Sun, Pucheng Gui, Zijian Yu, Pingkun Zhou
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cell & Bioscience
Subjects:
miRNA
HBV
HCC
Carcinogenesis
Online Access:http://link.springer.com/article/10.1186/s13578-020-00382-7

Internet

http://link.springer.com/article/10.1186/s13578-020-00382-7

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