Lamina-associated domains: peripheral matters and internal affairs

Lamina-associated domains: peripheral matters and internal affairs

Abstract At the nuclear periphery, associations of chromatin with the nuclear lamina through lamina-associated domains (LADs) aid functional organization of the genome. We review the organization of LADs and provide evidence of LAD heterogeneity from cell ensemble and single-cell data. LADs are typi...

Full description

Bibliographic Details
Main Authors: Nolwenn Briand, Philippe Collas
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Genome Biology
Subjects:
3D genome
Chromatin
LAD
Lamin A mutation
Nuclear envelope
Nuclear lamin
Online Access:http://link.springer.com/article/10.1186/s13059-020-02003-5

Internet

http://link.springer.com/article/10.1186/s13059-020-02003-5

Similar Items