Immunoelectron Microscopic Characterization of Vasopressin-Producing Neurons in the Hypothalamo-Pituitary Axis of Non-Human Primates by Use of Formaldehyde-Fixed Tissues Stored at −25 °C for Several Years

Immunoelectron Microscopic Characterization of Vasopressin-Producing Neurons in the Hypothalamo-Pituitary Axis of Non-Human Primates by Use of Formaldehyde-Fixed Tissues Stored at −25 °C for Several Years

Translational research often requires the testing of experimental therapies in primates, but research in non-human primates is now stringently controlled by law around the world. Tissues fixed in formaldehyde without glutaraldehyde have been thought to be inappropriate for use in electron microscopi...

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Bibliographic Details
Main Authors: Akito Otubo, Sho Maejima, Takumi Oti, Keita Satoh, Yasumasa Ueda, John F. Morris, Tatsuya Sakamoto, Hirotaka Sakamoto
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
vasopressin
corticotrophin-releasing factor
glutamate
paraventricular nucleus of the hypothalamus
Japanese macaque monkey
post-embedding immunoelectron microscopy
Online Access:https://www.mdpi.com/1422-0067/22/17/9180

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https://www.mdpi.com/1422-0067/22/17/9180

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