Efficient formation of inert Bi-213 chelates by tetraphosphorus acid analogues of DOTA: towards improved alpha-therapeutics

Efficient formation of inert Bi-213 chelates by tetraphosphorus acid analogues of DOTA: towards improved alpha-therapeutics

Abstract Background The recently growing interest in targeted alpha-therapy (TAT) calls for improvement of the labelling chemistry of the corresponding radionuclides. 213BiIII is a short-lived alpha emitter which emits only one alpha particle in its decay chain. Hence, it might be safer in applicati...

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Bibliographic Details
Main Authors: Jakub Šimeček, Petr Hermann, Christof Seidl, Frank Bruchertseifer, Alfred Morgenstern, Hans-Jürgen Wester, Johannes Notni
Format: Article
Language:English
Published: SpringerOpen 2018-08-01
Series:EJNMMI Research
Subjects:
Bismuth
Phosphonic acid
Phosphinic acid
Radiopharmaceuticals
Targeted alpha therapy
Online Access:http://link.springer.com/article/10.1186/s13550-018-0431-3

Internet

http://link.springer.com/article/10.1186/s13550-018-0431-3

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