Shear Stress Enhances the Paracrine-Mediated Immunoregulatory Function of Human Periodontal Ligament Stem Cells via the ERK Signalling Pathway

Shear Stress Enhances the Paracrine-Mediated Immunoregulatory Function of Human Periodontal Ligament Stem Cells via the ERK Signalling Pathway

Relevant immunomodulatory effects have been proposed following allogeneic cell-based therapy with human periodontal ligament stem cells (hPDLSCs). This study aimed to examine the influence of shear stress on the immunosuppressive capacity of hPDLSCs. Cells were subjected to shear stress at different...

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Bibliographic Details
Main Authors: Ravipha Suwittayarak, Nuttha Klincumhom, Utapin Ngaokrajang, Worachat Namangkalakul, João N. Ferreira, Prasit Pavasant, Thanaphum Osathanon
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
immunosuppression
IDO
TGF-β1
periodontal ligament stem cells
shear stress
T cells
Online Access:https://www.mdpi.com/1422-0067/23/13/7119

Internet

https://www.mdpi.com/1422-0067/23/13/7119

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