Renal and liver impairment in patients receiving cytotoxic chemotherapy

Chemotherapeutic agents can affect the glomerulus, renal tubules, interstitium or microvasculature. In renal impairment, drug excretion pathways by glomerular filtration and tubular secretion are inhibited, leading to increased systemic toxicity. Dose reductions were required in many drugs based on...

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Bibliographic Details
Main Authors: Nungrutai Saeaib, Arunee Dechaphunkul, Patrapim Sunpaweravong
Format: Article
Language:English
Published: Prince of Songkla University 2010-02-01
Series:Journal of Health Science and Medical Research (JHSMR)
Subjects:
Online Access:https://www.jhsmr.org/index.php/jhsmr/article/view/339