Renal and liver impairment in patients receiving cytotoxic chemotherapy
Chemotherapeutic agents can affect the glomerulus, renal tubules, interstitium or microvasculature. In renal impairment, drug excretion pathways by glomerular filtration and tubular secretion are inhibited, leading to increased systemic toxicity. Dose reductions were required in many drugs based on...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Prince of Songkla University
2010-02-01
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Series: | Journal of Health Science and Medical Research (JHSMR) |
Subjects: | |
Online Access: | https://www.jhsmr.org/index.php/jhsmr/article/view/339 |