Synaptic maturation at cortical projections to the lateral amygdala in a mouse model of Rett syndrome.

Rett syndrome (RTT) is a neuro-developmental disorder caused by loss of function of Mecp2--methyl-CpG-binding protein 2--an epigenetic factor controlling DNA transcription. In mice, removal of Mecp2 in the forebrain recapitulates most of behavioral deficits found in global Mecp2 deficient mice, incl...

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Bibliographic Details
Main Authors: Frédéric Gambino, Malik Khelfaoui, Bernard Poulain, Thierry Bienvenu, Jamel Chelly, Yann Humeau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2896423?pdf=render