MicroRNA-146b protects kidney injury during urinary tract infections by modulating macrophage polarization

ABSTRACTUrinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) can lead to severe kidney injury. However, the molecular mechanisms underlying the pathological process of kidney injury are still incompletely understood. In the present study, we demonstrate that microRNA-146b...

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Bibliographic Details
Main Authors: Changying Wang, Hongyan Cheng, Fenglian Yan, Hui Zhang, Junfeng Zhang, Chunxia Li, Mingsheng Zhao, Dongmei Shi, Huabao Xiong
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02094-23