Extrinsic cell death pathway plasticity: a driver of clonal evolution in cancer?
Abstract Human cancers are known to adhere to basic evolutionary principles. During their journey from early transformation to metastatic disease, cancer cell populations have proven to be remarkably adaptive to different forms of intra- and extracellular selective pressure, including nutrient scarc...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-11-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-022-01251-7 |