Mycobacterium PPE31 Contributes to Host Cell Death

Mycobacterium PPE31 Contributes to Host Cell Death

Genome scale mutagenesis identifies many genes required for mycobacterial infectivity and survival, but their contributions and mechanisms of action within the host are poorly understood. Using CRISPR interference, we created a knockdown of ppe31Mm gene in Mycobacterium marinum (M. marinum), which r...

Full description

Bibliographic Details
Main Authors: Siyuan Feng, Zhongsi Hong, Guoliang Zhang, Jiachen Li, Guo-Bao Tian, Haibo Zhou, Xi Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
virulence factors
PPE31
cell death
Mycobacterium tuberculosis
JNK signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.629836/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.629836/full

Similar Items