Computational inference of chemokine-mediated roles for the vagus nerve in modulating intra- and inter-tissue inflammation

Computational inference of chemokine-mediated roles for the vagus nerve in modulating intra- and inter-tissue inflammation

Introduction: The vagus nerve innervates multiple organs, but its role in regulating cross-tissue spread of inflammation is as yet unclear. We hypothesized that the vagus nerve may regulate cross-tissue inflammation via modulation of the putatively neurally regulated chemokine IP-10/CXCL10.Methods:...

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Bibliographic Details
Main Authors: Ashti M. Shah, Ruben Zamora, Derek Barclay, Jinling Yin, Fayten El-Dehaibi, Meghan Addorisio, Tea Tsaava, Aisling Tynan, Kevin Tracey, Sangeeta S. Chavan, Yoram Vodovotz
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Systems Biology
Subjects:
vagus nerve
vagotomy
inflammation
chemokines
systems biology
Online Access:https://www.frontiersin.org/articles/10.3389/fsysb.2024.1266279/full

Internet

https://www.frontiersin.org/articles/10.3389/fsysb.2024.1266279/full

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