4395 alpha-Synuclein Induced Reactive Gliosis

OBJECTIVES/GOALS: Reactive gliosis is a hallmark of neurodegenerative disease and is characterized by the release of pro-inflammatory cytokines and physiologic changes to glial cells. Our work identifies a novel inflammatory glial-glial cell interaction and role for mGluR5 that has the potential to...

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Bibliographic Details
Main Authors: Sean David Carey, Sarah Alshawi, Mondona McCann, Kathleen Maguire-Zeiss
Format: Article
Language:English
Published: Cambridge University Press 2020-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866120000527/type/journal_article