Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donorsResearch in context

Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donorsResearch in context

Summary: Background: The CC chemokine receptor 5 (CCR5) is a suggested receptor for Staphylococcus aureus leukotoxin ED. Homozygosity for the Δ32 deletion (CCR5Δ32) protects against human immunodeficiency virus infection and possibly also against leukotoxin ED. We examined the impact of CCR5Δ32 on...

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Bibliographic Details
Main Authors: Khoa Manh Dinh, Kathrine Agergård Kaspersen, Susan Mikkelsen, Bertram Dalskov Kjerulff, Jens Kjærgaard Boldsen, Mikkel Steen Petersen, Kristoffer Sølvsten Burgdorf, Erik Sørensen, Bitten Aagaard, Barbara Forman-Ankjær, Mie Topholm Bruun, Karina Banasik, Thomas Folkmann Hansen, Mette Nyegaard, Palle Duun Rohde, Søren Brunak, Henrik Hjalgrim, Sisse Rye Ostrowski, Ole Birger Pedersen, Henrik Ullum, Lise Tornvig Erikstrup, Christian Erikstrup
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:EBioMedicine
Subjects:
Staphylococcus aureus
Nasal carriage
CCR5Δ32 polymorphism
Infection susceptibility
Chemokine receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424004420

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http://www.sciencedirect.com/science/article/pii/S2352396424004420

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