Frequency of PGP and MRPA efflux pump genes in drug resistance in clinical isolates of Leishmania tropica and L. major

This study aimed to identify PGP and MRPA genes in clinical isolates of Leishmania. The genes of pgpa (MRPA) and mdr1 (PGP) are involved in the drug resistance, their products act as dependent transporters of ATP (ABC Transporter) in the reflux of drugs from the cytosol to the outer space of the cel...

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Bibliographic Details
Main Authors: Maede Parishan, Mahmoud Nateghi
Format: Article
Language:English
Published: Kharazmi University 2023-03-01
Series:یافته‌های نوین در علوم زیستی
Subjects:
Online Access:http://nbr.khu.ac.ir/article-1-3486-en.html